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Weight loss programs may soon be tailored to genetic makeup

Weight loss programs may soon be tailored to genetic makeup

"I think within five years, we'll see people start to use a combination of genetic, behavioral and other sophisticated data to develop individualized weight management plans", said Molly Bray from the University of Texas at Austin.

Scientists revealed personalized diets will be available in the next few years.

Bray believes the routine obesity diagnosis and treatment regimen may include patients submitting saliva samples for gene sequencing, and collecting data on patients' environment, diet, activity, and stress from portable monitors such as FitBits. Subsequently, the data will be fed into a computer algorithm to develop specific programs for over-weight people to achieve their target weight.

Emerging research is delving into genetic factors that lead individuals to have a variety of difference weight loss experiences, and that research could soon lead to new weight loss strategies. It's becoming less expensive to perform genomic sequencing, a key tool that researchers will need to investigate which genes stimulate weight gain. However, little is known about the genes that determine why some people lose weight more easily than others.


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'But the stats on long-term weight loss are pretty dismal. "We still don't understand the process of weight regain very well, either from a behavioral or a biological standpoint".

Scientists are already aware of some of the genetic basis for weight-related disease. A recent summary report on the genetics of weight loss, developed by some of the leading experts in this field, finds that the biggest challenge to realizing this dream is the need for better analytical tools for discovering the relationships between genetics, behavior and weight-related diseases.

'When you go back and see how much of the variation in this gene accounts for the variation in body size in the general population, it's really small, ' she said. "There are going to be several genes involved with obesity, and they're going to interact with each other in complicated ways".

'And that's certainly true of weight loss and maintenance too'.

"Obesity is one of the gravest problems of our times", Bray said.

Previous studies have shown that almost half of the variation in a person's body mass index can be attributed to genetic factors.

Meanwhile, the rest is due to environmental factors - such as diet and exercise. For example, depending on a person's specific genetic makeup, exercise might be less effective at reducing weight for some people compared with others.

"For clinicians, better understanding of the genetic underpinnings for individual patients could aid in the development of precision weight-loss treatments with dietary, physical activity and other methods customized to each individual", the news release stated.

'They actually say, "Oh thank you".

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Kirjoitettu Saturday 26.12.2015

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